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李松

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 个人资料

 

姓名:李   出生年月:19804 

性别:男       学历:研究生   专业学位:博士

专业:生物医学工程   籍贯:江苏徐州   婚姻状况:已婚        

联系电话:+86-731-22182107   15162171928

E-mailsosong1980@gmail.com

受教育经历

2005/09~2008/07   东南大学生物电子学国家重点实验室   博士    

2002/09~2005/07   东南大学生物电子学国家重点实验室  硕士  

1998/09~2002/07    东南大学                 学士

工作、研究经历

2004/03~2008/10   湖南工业大学绿色包装与生物纳米技术应用省重点实验室    

2008/10~2012/03   美国哈森生物技术研究中心   博士后

2012/04~2015/01   美国哈森生物技术研究中心   高级研究员

2015/01~2017/07    美国iCubate 公司            资深研发科学家

2017/01~          美国iRepertoire 公司            资深研发科学家

2010/11~2019/01     湖南工业大学                    副研究员

2019/02~            湖南工业大学                    教授

长期从事核酸分子诊断技术和高通量生物传感方面的研究,具有比较丰富的相关科研经验,发表相关研究论文100余篇,累计影响因子超过400,正面他引超过3000, H指数28主持和参与国家重点研发计划,973项目,国家自然科学基金及其他省部级课题10余项。入选2019年科睿唯安全球高被引科学家。最早在国际上提出基于磁性纳米颗粒的高通量核酸自动化检测技术,并被收入专业工具书。历任美国Hudsonalpha生物技术研究中心、iCubate公司和iRepertoire公司资深科学家,参与发展了新一代“全自动多重分子诊断系统”——“iCubate”系统及其配套试剂盒并且获得FDA认证。完成全世界首套全自动、全封闭NGS文库制备系列试剂盒及系统的开发。

学术兼职

副主编

Material Express

Nanoscience and Nanotechnology Letters

Journal of Biomedical Nanotechnology

编委

纳米生物医学工程

中国化学快报

会员

美国化学会会员

欧洲免疫遗传学联合会

中国生物医学工程学会

中国免疫学会

审稿专家

Biosensor and Bioelectronics, Elsevier

Diagnostic Microbiology and Infectious Disease, Elsevier

Analytica Chimica Acta, Elsevier

Applied Microbiology and Biotechnology, Springer

Journal of Biomedical and Nanobiotechnology, American Scientific Publishers

Journal of Nanoscience and Nanotechnology, American Scientific Publishers

RSC Advances, Royal Society of Chemistry

Analyst, Royal Society of Chemistry

Nanomedicine: Nanotechnology, Biology, and Medicine, Elsevier

发表部分研究论著

1. Ziyu He , Zhu Chen , Miduo Tan, Sauli Elingarami, Yuan Liu, Taotao Li, Yan Deng, Nongyue He, Song Li *, Juan Fu*, Wen Li. (2020) A Review on Methods for Diagnosis of Breast Cancer Cells and Tissues, Cell Proliferation. 53:e12822.

2. Hongming Dong, Congli Tang, Ziyu He, Hongmei Liu, Yuyue Xu, Hao Huang, Gaojian Yang, Ziqi Xiao, Song Li,*, Yan Deng, Zhu Chen, Hui Chen, Zuodong Qin, Yasser Perera Negrin, Nongyue He*. (2020) Rapid identification of diarrheagenic Escherichia coli based on barcoded magnetic bead hybridization, Chinese Chemical Letters.31(7):1812-1816

3. Congli Tang, Ziyu He, Hongmei Liu, Yuyue Xu, Hao Huang, Gaojian Yang, Ziqi Xiao, Song Li*, Hongna Liu, Yan Deng, Zhu Chen, Hui Chen, Nongyue He. (2020) Application of magnetic nanoparticles in nucleic acid detection, Journal of Nanobiotechnology.18: 62.

4. Xuefeng Niu, Song L, Pingchao Li, Wenjing Pan, Qian Wang, Ying Feng, Xiaoneng Mo, Qihong Yan, Xianmiao Ye 4 , Jia Luo 4 , Linbing Qu 4 , Daniel Weber 3 ,Miranda L. Byrne-Steele 3 , Zhe Wang 2 , Fengjia Yu 2 , Fang Li 6 , Richard M. Myers 5 ,Michael T. Lotze 7 , Nanshan Zhong 1 , Jian Han 2,3,5 * and Ling Chen 1,4,6 *2020Longitudinal Analysis of T and B Cell Receptor Repertoire Transcripts Reveal Dynamic Immune Response in COVID-19 Patients.Frontiers in Immunology, 11:582010.

5. Liu H, Heflin K, Han J, Conover M, Wagner L, Bertrand J, Ewing P, Lu S, Clemmons S, Watts J, Li S*. Development of the iCubate Molecular Diagnostic Platform Utilizing Amplicon Rescue Multiplex Polymerase Chain Reaction. (2019) J Biomed Nanotechnol. 15(7):1598-1608.

6. Ziyu He, Congli Tang, Xiang Chen, Hongmei Liu, Gaojian Yang, Ziqi Xiao, WenLi, Yan Deng, Lian Jin, Hong Chen, Zhu Chen, Song Li*. (2019) Based on magnetic beads to develop the kit for extraction of high-quality cell-free DNA from blood of breast cancer patients, Materials Express. 6: 956-961.

7. Shang-Gin Wu, Wenjing Pan, Hongna Liu, Miranda L. Byrne-Steele, Brittany Brown, Mollye Depinet, Xiaohong Hou, Jian Han, Song Li*. (2019) High-throughput sequencing of T-cell receptor repertoire using dry blood spots, Journal of Translational Medicine,.17:74.

8. Chunming Zhang 1 , Yanping Huang 1 , Yile Fang 1 , Pei Liao 1 , Yanqi Wu 3 , Hui Chen 2 , Zhu Chen 2 ,Yan Deng 2 , Song Li 2 , Hongna Liu 2 , and Nongyue He 1,2,∗.(2019)The Liquid Level Detection System Based on Pressure Sensor. Journal of Nanoscience and Nanotechnology,19(11):2049-2053

9. Yuxuan Lai1, Hao Huang1, Zhihuan Xia2, Song Li1, Yan Deng1,∗,and Xueying Liu1,∗.(2019)A sandwich-type electrochemical immunosensor using polythionine/AuNPs nanocomposites as label for ultrasensitive detection of carcinoembryonic antigen. Materials Express.9(5):444-450.

10. Ziqi Xiao1, Gaojian Yang1, Deng Yan1, Song Li1, Zhu Chen1, Wen Li1, Yanqi Wu 1,2, and Hui Chen 1,∗(2019).Effects of diverse materials-based methods on DNA extraction for Clostridium difficle from stool samples. Materials Express.9(5):509-516.

11. Xiaocheng Yu a,† , Lei He a,† , Myima Pentok d,† , Haowen Yang f , Yale Yang a , Zhiyang Li c , Nongyue Hea,b, *, Yan Deng b, *, Song Li b, Tonghua Liu d,e, *, Xiangyu Chengand Huiwen Luoh.(2019)An aptamer-based new method for competitive fluorescence detection. Nanoscale,2019,11.

12. Liu Hongna, Heflin Kathryn, Han Jian, Conover Matt, Wagner Leslie, Bertrand Jeff; Ewing Phillip, Lu Stanley, Clemmons Scott, Watts John, Li Song. (2019)Development of the iCubate Molecular Diagnostic Platform Utilizing Amplicon Rescue Multiplex Polymerase Chain Reaction. Journal of biomedical nanotechnology, 15(7): 1598-1608.

13. Liao Pei, Fang Yile, Chen Hui, Wu Yanqi, Deng Yan, Chen Zhu, He Nongyue, Liu Hongna, Li, Song . (2019)QuickAnalysis: A software designed and developed for a portable on-site pathogen detection system. Journal of nanoscience and nanotechnology, 19(4): 2054-2059.

14. Chen Zhu, Yang Tong, Yang Haowen, Li Taotao, Nie Libo, Mou Xianbo, Deng Yan, He Nongyue, Li Zhiyang, Wang Lijun, Li Song*. (2018) A PortableMulti-Channel Turbidity System for Rapid Detection of Pathogens byLoop-Mediated Isothermal Amplification , Journal of Biomedical Nanotechnology, 4(1): 198~205

15. Liu Hongna, Dong Hongming, Chen Zhu, Lin Lin, Chen Hui, Li Song, Deng Yan.(2017) Magnetic nanoparticles enhanced microarray detection of multiple foodborne pathogens[J]. Journal of Biomedical Nanotechnology, 13(10): 1333-1343.

16. Song Li, Hongna Liu, YingyingJia, Yan Deng, Liming Zhang, Zhuoxuan Lu, Nongyue He. (2012). A Novel SNPs Detection Method Based on Gold Magnetic Nanoparticles Array and Single Base Extension. Theranostics, 2(10): 967-975. ( ESI高引论文)

17. Yuanying Zhang, Hongna Liu, Yingying Jia, Yan Deng, Song Li*, Nongyue He*. (2015) A Magnetic Nanoparticles-Based Combination Detection of COX-2 and BCL-2 Polymorphisms Associated with Gastric Cancer SusceptibilityScience of Advanced Materials,7(3): 532-539.

18. Sauli Elingarami, Hongna Liu, Aneth Kalinjuma, Weiyue Hu, Song Li*, Nongyue He*. (2015) Polymorphisms in NEIL-2, APE-1, CYP2E1 and MDM2 Genes are Independent Predictors of Gastric Cancer Risk in a Northern Jiangsu Population (China). Journal of Nanoscience Nanotechnology, 15(7):4815-28.

19. *Song Li, Hongna Liu, YingyingJia, XianboMou, Yan Deng, Lin Lin, Bin Liu, Nongyue He. (2013). An Automatic High-throughput SNP Genotyping Approach Based on Universal Tagged Arrays and Magnetic Nanoparticles. Journal of Biomedical Nanotechnology, 9(4):689-98. 

20. Yuan Liu, Yuxuan Lai, Gaojian Yang, Congli Tang, Yan Deng*, Song Li*, and Zunliang Wang. (2017) Cd-Aptamer Electrochemical Biosensor Based on AuNPs/CS Modified Glass Carbon Electrode, Journal of Biomedical Nanotechnology, 13, 1253-1259.

21. *Song Li, Hongna Liu, Yan Deng, Lin Lin, Nongyue He. (2013). Development of A Magnetic Nanoparticles Microarray for Simultaneous and Simple Detection of Foodborne Pathogens. Journal of Biomedical Nanotechnology, 9(7):1254-1260.

22. Lan Tian, Song Li, Hongna Liu, Zhifei Wang, Nongyue He. (2009) An automated MagStation for high-throughput single nucleotide polymorphism genotyping and the dual-color hybridization. Journal of Biomedical Nanotechnology, 5(5):511-515. (co-first author)

23. Hongna Liu, Song Li, Lishang Liu, Lan Tian, NongyueHe. (2010) An integrated and sensitive detection platform for biosensing application based on Fe@ Au magnetic nanoparticles as bead array carries. Biosensors and Bioelectronics, 26(4):1442-1448. (co-first author)

24. Hongna Liu, Song Li, Zhifei Wang, Meiju Ji, Libo Nie, Nongyue He. (2007) High-throughput SNP genotyping based on solid-phase PCR on magnetic nanoparticles with dual-color hybridization. Journal of Biotechnology. 131(3): 217-222. (co-first author)

25. Hongna Liu, Song Li, Zhifei Wang, YafeiGuo, Nongyue He. (2008) Automated detection system of single nucleotide polymorphisms using two kinds of functional magnetic nanoparticles. Applied Surface Science, 255(2): 600-603. (co-first author)

26. Song Li, Hongna Liu, Zhifei Wang, Peng Hou, Yafei Guo, Quanguo He, Nongyue He. (2006) Magnetic-particles-based high-throughput genotyping method with dual-color Fluorescence hybridization. Analytical Biochemistry, 359(2): 277-279.

27. Song Li, Hongna Liu, Lishang Liu, Lan Tian, Nongyue He. (2010) A novel automated assay with dual-color hybridization for single-nucleotide polymorphisms genotyping on gold magnetic nanoparticle array. Analytic Biochemistry, 405(1):141-143.

28. Song Li, Hongna Liu, Lishang Liu, Nongyue He. (2010) Covalent binding of streptavidin on gold magnetic nanoparticles for bead array fabrication. Journal of Nanoscience and Nanotechnology, 10(8): 4875-4882.

29. Song Li, Meiju Ji, Nongyue He, Zuhong Lu. (2007) Application of Microarray-Based Method for Methylenetetrahydrofolate Reductase (MTHFR) Polymorphisms in the Risk of Gastric Carcinoma in East China Population. Journal of Nanoscience and Nanotechnology, 7(9): 3245-3249. 

30. Hongna Liu, Song Li, Lishang Liu, Lan Tian, Nongyue He. (2010) A Novel Single Nucleotide Polymorphisms Detection Sensors Based on Magnetic Nanoparticles Array and Dual-Color Single Base Extension. Journal of Nanoscience and Nanotechnology, 10(8): 5311-5315. 

31. Hongna Liu,Song Li, Zhifei Wang, Peng Hou, Quanguo He. (2008) Fabrication and Application of Single Nucleotide Polymorphisms Library on Magnetic Nanoparticles Using Adaptor PCR. Journal of Nanoscience and Nanotechnology, 8(1): 405-409.

32. Song Li, Meiju Ji, Peng Hou, Nongyue He, Hong Chen. (2006) Application of micro array-based method for functional SNP genotyping in the risk of gastric carcinoma in Chinese population.Rare Metal Materials and Engineering. 35:467-470.

33. Song Li, Hongna Liu, Zhifei Wang, Meiju Ji, Yafei Guo, Nongyue He, Yabin Dai.(2007) A novel in situ magnetic particle PCR based high-throughput genotyping method using universal tags. Progress in Biochemistry and Biophysics, 34 (10): 1107-1112.

34. Hongna Liu, Song Li, Zhifei Wang, Peng Hou, Quanguo He, Nongyue He.(2007) PCR Amplification on Magnetic Nanoparticles: Application for High-throughput Single Nucleotide Polymorphism Genotyping, Biotechnology Journal, 2(4): 508-511.

35. Lijian Xu, Li Gao, *Song Li, Jingjing Du, He Nongyue, Hongna Liu, Ting Wang.(2009) Self-assembly monolayer of 3-aminopropylmethyldiethoxysilane on glassy carbon electrode for albumin detection. Journal of Nanoscience and Nanotechnology. 9(3):1923-1927. 

36. Lishang Liu, Hongna Liu, *Song Li, Yan Deng, Xiaolong Li, Nongyue He. (2010) Fabrication and Characterization of Streptavidin gamma-Fe2O3@Au Nanocomposites for Biological Application, Acta Chimica Sinica, 68(20): 2041-2046.

37. Yuanying Zhang, Hongna Liu, Yingying Jia, Yan Deng, *Song Li, Nongyue He. (2015)A Magnetic Nanoparticles-Based Combination Detection of COX-2 and BCL-2 Polymorphisms Associated with Gastric Cancer SusceptibilityScience of Advanced Materials 7(3): 532-539.

38. Zunliang Wang, Song Li, NongyueHe. (2009)Effect of single central base pair mismatch on the conformation and stability of surface immobilized DNA: molecular dynamics studies, Journal of Nanoscience and Nanotechnology,9(11): 6465-6469. 

39. Hongna Liu, Song Li, Lishang Liu, Yan Deng, Zhiyang Li, Nongyue He.(2009) Magnetic Particle-based Single Nucleotide Polymorphism Detection Method Using Linker-Polymerase Chain Reaction. Acta Chimica Sinica. 67(15): 1797-1802.

40. Nongyue He, Song Li, Hongna Liu. (2009) High-Throughput SNP Detection Based on PCR Amplification on Magnetic Nanoparticles Using Dual-Color Hybridization. Single Nucleotide Polymorphisms Methods and Portocols 2nd Edition, Methods in Molecular Biology, 2009, 578, 393-402.

41. Hongna Liu, Song Li, Lishang Liu, Lan Tian, NongyueHe. (2009) Multiplex single nucleotide polymorphisms genotyping using solid-phase single base extension on magnetic nanoparticles. Analytic Biochemistry, 386(1):126-128.

42. 刘洪娜, 李松, 刘丽赏, 田岚, 贾英英, 李智洋, 邓燕, 何农跃.(2010) 基于磁性颗粒微阵列与双色荧光杂交的单核苷酸多态性分型方法研究,分析化学, 38(12): 1708-1713SCI

43. Rasheed Ahmad, Juan Fu, Nongyue He, Song Li. (2016) Advanced Gold Nanomaterials for Photothermal Therapy of Cancer. Journal of Nanoscience and Nanotechnology, 16(1):67-80.

44. Xianbo Mou, Zeeshan Ali, Song Li, Nongyue He. (2015) Applications of Magnetic Nanoparticles in Targeted DrugDelivery System, Journal of Nanoscience Nanotechnology, 15(1): 54-62

45. Ming Liu, Ping Hu, Gen Zhang, Yu Zeng, Haowen Yang, Jing Fan, Lian Jin, Hongna Liu, Yan Deng, Song Li, Xin Zeng, Sauli Elingarami, Nongyue He. (2015) Copy number variation analysis by ligation-dependent PCR based on magnetic nanoparticles and chemiluminescence.Theranostics, 5(1):71-85.

46. Jing Fan, Haowen Yang, Ming Liu, Dan Wu, Hongrong Jiang, Xin Zeng, Sauli Elingarami, Zhiyang Li, Song Li, Hongna Liu, Nongyue He.(2015) Fluorescent Quantification of DNA Based on Core-Shell Fe3O4@SiO2@Au Nanocomposites and Multiplex Ligation-Dependent Probe AmplificationJournal of Nanoscience Nanotechnology,  15(2): 1123-1129.

47. Sauli Elingarami, Hongna Liu, Aneth Kalinjuma, Weiyue Hu, Song Li, Nongyue He. (2015) Polymorphisms in NEIL-2, APE-1, CYP2E1 and MDM2 Genes are Independent Predictors of Gastric Cancer Risk in a Northern Jiangsu Population (China). Journal of Nanoscience Nanotechnology, 15(7):4815-28

48. Yun Xia, Yanqi Wu, Bobo Zhang, Zhiyang Li, Nongyue He, Song Li.(2015) Wireless Falling Detection System Based on Community. Journal of Nanoscience Nanotechnology, 15(6):4367-72.

49. Liming Zhang, Kai Xia, Deng Y, Song Li, Chuanxiang Zhang C, Zhuoxuan Lu, Nongyue He. (2014) Methoxy poly(ethylene glycol) conjugated doxorubicin micelles for effective killing of cancer cells.Journal of Nanoscience Nanotechnology, 14(8):6458-60.

50. Liming Zhang, Zhixin Wang, Zhuoxuan Lu, Kai Xia, Yan Deng, Song Li, Chuanxiang Zhang, Yuanfu Huang, Nongyue He. (2014) Synthesis of LiYF4:Yb, Er upconversion nanoparticles and its fluorescence properties. Journal of Nanoscience Nanotechnology,14(6):4710-3.

51. Bin Liu, Yingying Jia, Man Ma, Zhiyang Li, Hongna Liu, Song Li, Yan Deng, Liming Zhang, Zhuoxuan Lu, Wei Wang, Nongyue He. (2013). High Throughput SNP Detection System Based on Magnetic Nanoparticles Separation. Journal of Biomedical Nanotechnology, 9(2): 247-256. 

52. Zhiyang Li, Haowen Yang, Nongyue He, Wenbiao Liang, Chao Ma, Muhammad Ali A Shah, Yongjun Tang, Song Li, Hongna Liu, Hesheng Jiang, Yafen Guo. (2013). Solid-phase hybridization efficiency improvement on the magnetic nanoparticle surface by using dextran as molecular arms. Journal of Biomedical Nanotechnology, 9(11):1945-9. 

53. Nongyue He, Xianbo Mou, Yan Deng, Hongna Liu, Song Li, Lijian Xu, Xiaolong Li. (2012). Conditions of polymerase chain reaction amplification by magnetic enrichment and nanoscale detection sensitivity. Journal of Nanoscience and Nanotechnology, 12(5):3862-3866.

54. Zhuoxuan Lu, Liming Zhang, Yan Deng, Song Li, Nongyue He. (2012). Grapheneoxide for rapid microRNA detection. Nanoscale, 4(19):5840-5842. 

55. Yan Deng, Keke Liu, Yuan Liu, Hongming Dong, Song Li.(2016) An Novel Acetylcholinesterase Biosensor Based on Nano-Porous Pseudo Carbon Paste Electrode Modified with Gold Nanoparticles for Detection of Methyl Parathion. Journal of Nanoscience and Nanotechnology. 16(9):9460-9467.

56. Zhiyang Li, Lei He, Nongyue He, Yan Deng, Zhiyang Shi, Hua Wang, Song Li, Hongna Liu, Zhifei Wang, Daxin Wang. (2011) Polymerase Chain Reaction Coupling with Magnetic Nanoparticles-Based Biotin-Avidin System for Amplification of Chemiluminescent Detection Signals of Nucleic Acid. Journal of Nanoscience and Nanotechnology, 11(2):1074-1078. 

57. Matthew D Huff, David Weisman, John Adams, Song Li, Jessica Green, Leslie L Malone and Scott Clemmons.(2014) The frequency of tetracycline resistance genes co-detected with respiratory pathogens: a database mining study uncovering descriptive trends throughout the United States. BMC Infectious Diseases, 14: 460.

58. Zhiyang Li, Lei He, Nongyue He, Zhiyang Shi, Hua Wang, Song Li, Hongna Liu, Xiaolong Li, Yabin Dai, Zhifei Wang. (2010) Chemiluminescent detect of E. coli O157:H7 using immunological method based on magnetic nanoparticles. Journal of Nanoscience and Nanotechnology. 10(2): 696-701. 

59. Hongna Liu, Song Li, Lishang Liu, Lan Tian, Yingying Jia, Zhiyang Li, Yan Deng, Nongyue He, (2010) Single Nucleotide Polymorphism Genotyping Based on Magnetic Bead Array and Dual-color Hybridization, Chinese Journal of Analytical Chemistry , 38(12):1708-1713.

60. Xianbo Mou, Taotao Li, Jiuhai Wang, Zeeshan Ali, Yuanying Zhang, Zhu Chen, Yan Deng, Song Li, Enben Su, Qiongying Jia, Nongyue He, Jian Ni, Daxing Cui.(2015) Genetic Variation of BCL2 (rs2279115), NEIL2 (rs804270), LTA (rs909253), PSCA (rs2294008) and PLCE1 (rs3765524, rs10509670) Genes and Their Correlation to Gastric Cancer Risk Based on Universal Tagged Arrays and Fe3O4 Magnetic Nanoparticles. Journal of Biomedical Nanotechnology. 2015 Nov;11(11):2057-66.

61. Nongyue He, Lijian Xu, Ting Wang, Jingjing Du, Zhiyang Li, Yan Deng, Song Li, Shuxun Ge. (2009). Determination of Paracetamol with Porous Electrochemical Sensor. Journal of Biomedical Nanotechnology, 5(5):607-610. 

62. Zhiyang Li, Lei He, Zhiyang Shi, Song Li, Hongna Liu, Zhifei Wang, Nongyue He. (2009) Preparation of SiO2/polymethyl methacrylate/Fe3O4 nanoparticles and its application in detecting E. coli O157:H7 using chemiluminescent immunological method. Journal of Biomedical Nanotechnology, 5(5): 505-510.

63. Libo Nie, Yun Yang, Song Li, Nongyue He. (2007) Enhanced DNA detection based on the amplification of gold nanoparticles using quartz crystal microbalance. Nanotechnology, 18 (30): 305501

64. Hongna Liu, Song Li, Zhifei Wang, Nongyue He, Quanguo He. (2007) High-throughput SNP genotyping method with PCR on magnetic nanoparticles. Chemical Journal of Chinese Universities, 28(6): 1035-1038.

65. Jianxin Tang, Nongyue He, Song Li, Hong Chen, (2007) In Situ Synthesis of DNA Micro-arrays Using Typography Technique, Science in China Series B. 50 (1): 75-83

66. Libo Nie, Yun Yang, Song Li, Jiqing Wang, and Qinglin Hou. (2007) QCM Detection of Oligonucleotide by Quiescent Mode and Flowing Mode. Journal of Nanoscience and Nanotechnology. 7(8): 2927–2929. 

67. Meiju Ji, Peng Hou, Song Li, Nongyue He, and Zuhong Lu. (2004) Colorimetric silver detection of methylation using DNA microarray coupled with linker-PCR. Clinica Chimica Acta. 342: 145-153.

68. Peng Hou, MeijuJi, Song Li, Nongyue He, and Zuhong Lu. (2004) High-throughput method for detecting DNA methylation. Journal of Biochemical and Biophysical Methods. 60(2): 139-150.

69. Peng Hou, Meiju Ji, Song Li, Nongyue He, and Zuhong Lu. (2004) Microarray-Based Approach for High-Throughput Genotyping of Single-Nucleotide Polymorphisms with Layer-by-Layer Dual-Color Fluorescence Hybridization. Clinical Chemistry. 50(10): 1955-1957.

70. Meiju Ji, Peng Hou, Song Li, Nongyue He, Zhenyu Cao, Zuhong Lu. (2004) Microarray-based method for genotyping of functional single nucleotide polymorphisms using dual-color fluorescence hybridization. Mutation Research. 548: 97-105.

71. Peng Hou, Meiju Ji, Cunwang Ge, Jiayao Shen, Song Li, Nongyue He, and Zuhong Lu. (2003) Detection of methylation of human p16Ink4a gene 5’-CpG islands by electrochemical method coupled with linker-PCR. Nucleic Acids Res. 31(16): e92. 

72. JianXin Tang, Song Li, ZhengChun Liu, Libo Nie, Pengfeng Xiao, Zuhong Lu, Nongyue He. (2003) Surface Modification of Polypropylene Microporous Membrane by Plasma and Its Application for the in situ Oligonucleotide Synthesis, Acta Chimica Sinica, 61 (4): 641-645.

73. Zhifei Wang, Yafei Guo, Song Li, Sun Y, Nongyue He. (2008) Synthesis and characterization of SiO2/(PMMA/Fe3O4) magnetic nanocomposites. Journal of Nanoscience and Nanotechnology. 8(4):1797-802.

74. Ting Wang, Zhangqi Feng, Nongyue He, Zhifei Wang, Song Li, Yafei Guo, Lijian Xu.(2007) A novel preparation of nanocapsules from alginate-oligochitosan. Journal of Nanoscience and Nanotechnology. 7(12): 4571-4574. 

75. Lijian Xu, Jingjing Du, Nongyue He, Yan Deng, Song Li, Ting Wang. (2009). Anodic Stripping Voltammetry for Detection of DNA Hybridization with Porous Pseudo-Carbon Paste Electrode by Gold Nanoparticle-Catalyzed Silver Enhancement.  Journal of Nanoscience and Nanotechnology, 9(4): 2698-2703. 

主要科研项目

(1) 基于磁性纳米颗粒与全自动卡盒的个体化免疫组库信息高通量获取方法研究(国家自然科学基金资助项目,项目批准号:61971187,课题负责人,2020

(2) 基于多组学研究筛选与鉴定新型冠状病毒感染患者疾病转归的外周血生物学标志物(湖南创新型省份建设专项资金(抗击新冠肺炎疫情应急专题)项目,项目批准号:2020SK3005,第四参与者,2020

(3) 基于磁性颗粒微阵列与单碱基循环延伸技术的高通量和自动化的SNP检测方法研究(国家自然科学基金,6080100720092011,主持完成)

(4) 基于磁性纳米颗粒与单碱基循环延伸技术的高通量自动化SNP分型技术(湖南省教育厅优秀青年项目,08B0182008-2010,主持完成)

(5) 基于磁性颗粒微阵列与单碱基循环延伸技术高通量和自动化的SNP检测方法研究 (中国博士后科学基金一类资助,200804301602008-2010,主持完成)

(6) 基于全基因组扩增和磁性纳米颗粒的高通量自动化SNP分型技术 (湖南省自然科学基金, 09JJ40042009-2010,主持完成)

(7) 胃癌相关基因的高通量单核苷酸多态性研究(国家重点基础研究发展计划(973计划)二级子课题,胃癌相关分子标志物载体定位、定量可视化的纳米技术的研究,2010CB9339032010-2014,主持完成)

(8) 基于纳米磁分离和化学发光的烈性病原体和重组病原体信息高通量获取(国家自然科学基金,906060272006-2008主要参与者

(9) 通用定量甲基化特异性PCRUni-Q-MSP)用于肿瘤相关基因甲基化谱分析(国家自然科学基金,306007362007-2009,主要参与者)

(10) 磁分离与发光纳米颗粒在快速获取病原信息中的增敏作用与应用研究(国家自然科学基金,605070322006-2008,主要参与者)

(11) 基于磁分离的多样本多位点高通量SNP检测技术(国家863“十一五计划项目,2006AA02Z1332006-2010,主要参与者)

(12) 纳米材料在烈性传染病病原快速检测中的增敏作用与应用研究(高等学校博士学科点专项科研基金,20050286014, 2006.1-2008.12,参与完成)

(13) 基于通用引物等温扩增和磁性颗粒介导聚合技术的高通量可视化个体核酸信息检测方法研究(国家自然科学基金面上项目,项目批准号:61571187,课题负责人,2016-2019

(14) 病原微生物快速高通量检测通用化纳米颗粒芯片技术研究(国家自然科学基金面上项目,项目批准号:61471168,课题主要参与者,2015-2018

(15) 基于磁性纳米颗粒应用的高通量、高灵敏、快速核酸分子诊断技术研究(湖南省自然科学基金面上项目,项目批准号:14JJ7063,课题负责人,2014-2017

(16) 基于通用滚环扩增技术的快速可视化高通量核酸分子检测方法研究(湖南省教育厅优秀青年项目,项目批准号:18B299,课题负责人,2019-2021

所获奖项

1. 何农跃, 李智洋, 李松, 柴忠心, 刘宾, 刘洪娜, 邓燕, 曾新, 王志飞, 王炜, 李小龙, 许利剑, 马超,基于磁性纳米颗粒的生物和医学新技术(2014年教育部高等学校科学技术进步奖二等奖

2. 何农跃,邓燕,吕卓璇,张立明,李松,刘洪娜,微纳尺度生物医学材料可控制备及生物医学应用 2016年湖南省自然科学奖二等奖)

3. 李智洋,何农跃,曾新,刘宾,李松张根,王志飞基于磁性纳米颗粒的生物医学新技术及应用 2014年南京市科学技术进步奖二等奖)

4. 生物芯片和生物纳米医学技术研究及应用(2017年株洲市首届科技创新奖)

5. 2020年CCL优秀青年学者

6. 2020年科睿唯安高被引科学家

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