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聂立波

文章来源: 作者: 发布时间:2021-06-27 14:08:33 点击数: 字号:

聂立波,女,1973年生,汉族,湖南宁乡人博士,教授,士生导师湖南工业大学生命科学与化学学院副院长。湖南省生物医学工程优秀研究生导师团队成员,湖南省化学化工学会理事,株洲市免疫学会常务理事,株洲市高层次人才。2001年毕业于湖南大学应用化学专业,获硕士学位;2005年毕业于东南大学生物医学工程专业,获博士学位;2008年中山大学化学博士后流动站出站。先后主持国家自然科学基金、863重点项目子课题、湖南省自然科学基金、中国博士后科学基金湖南省教育厅重点项目株洲市科技计划重点研发项目及多项横向课题,在国内外学术刊物上发表SCI收录学术论文50余篇,获发明专利1项,参编英文专著1部。

研究方向

1. 生物传感检测技术

2. 多功能纳米载药系统

主持科研项目:

1. 湖南省重点基于生物条形码/金标银染的肺癌细胞超灵敏液体活检19A144);

2. 湖南省自然科学基金,基于热/化疗-荧光/MRI成像的多功能靶向纳米载药系统2019JJ60058

3. 广东省材料学特色重点学科开放基金,响铃Fe3O4@mSiO2-AuNCs复合载药微球的研究

4. 株洲市科技计划重点研发项目,高强度碳纤维树脂基合新材料及关键术研

5. 广东省材料学特色重点学科开放基金,上转换纳米粒子/介孔二氧化硅/金纳米棒多功能载药系统CNXY2017009

6. 国家自然科学基金:基于磁分离与量子点荧光放大的胃癌早期诊断基因检测新方法61102031

7. 湖南省自然科学基金:宫颈癌早期诊断的DNA检测新方法研究11JJ5042

8. 863计划重点项目“超灵敏纳米多孔生物传感器件的研发与应用”子课题:流动态QCM传感器研发2007AA022007

9. 中国博士后科学基金:磁性/温敏/荧光多功能药物控释载体的研究,20070420797

10. 湖南省教育厅青年项目:纳米磁分离与荧光放大基因检测新方法的研究与应用06B022

11. 湖南省自然科学基金:纳米金放大的体声波基因芯片05jj40053

12. 湖南省教育厅项目:基于纳米金放大的压电体声波基因芯片研究04C722

代表性论文及著作:

1. Liang GongLan Zhao, Miduo Tan, Ting Pan, Huai He, Yulin Wang, Xuliang He, Wenjun Li, Li Tang, and Libo Nie*. Two-photon fluorescent nanomaterials and their applications in biomedicineJournal of Biomedical Nanotechnology, 2021175):509-528.

2. Yangyang Li, XiuzhenQiu, Yulin Wang, Huishi Guo, and Libo Nie*. Highly Selectivity Molecularly Imprinted Fluorescence Sensor Based on Carbon Quantum Dots for the Determination of Anthraquinones. Journal of Nanoscience and Nanotechnology, 2021, 21: 2109-2116.

3. Haji Chomba, Ting Pan, Xinyue Zhuo, Lan Zhao, Yulin Wang, Zhao Huang, Haikael Martin, Dongchu Chen, and Libo Nie*. A Bio-Barcode Electrochemical DNA Biosensor Based on Poly T30 Copper Nanoparticle Signaling. Science of

Advanced Materials, 2021, 13(2): 73-79.

4. Xiuzhen Qiu, Yangyang Li, Yulin Wang, Huishi Guo, Libo Nie. A novel molecularly imprinted nanosensor based on quartz crystal microbalance for specific recognition of α-amanitin, Microchemical Journal, 2020,159: 105383

5. Yulin Wang, XiuzhenQiu, Yangyang Li, Huishi Guo, Wenguan Lu, and Libo Nie. Synthesis of a Molecularly Imprinted Polymer on NH2 -MIL-101(Cr) for Specific Recognition of Diclofenac Sodium, Journal of Nanoscience and Nanotechnology, 2020,20: 1807-1813.

6. Pengfei Jiang, Miduo Tan, Lan Zhao, Yulin Wang, Ting Pan, Haji Chomba, Zhao Huang, Dongchu Chen, and Libo Nie*. A novel electrochemical DNA detection method based on bio-barcode/gold label silver stain dual amplificationMater. Express ,2020, 10(3): 206-213.

7. Pengfei Jiang, Chomba Haji, Xiufang Ye, Menglei Chang, Wenjun Li, Xuliang He, Dongchu Chen, and Libo Nie. A Novel Inductive Coupled Plasma Mass Spectrometry Gene Detection Method Based on AuNPs and Bio-Barcode Signal Amplification, Nanosci. Nanotechnol. Lett. 2019, 11(5): 638644.

8. Chenyang Ji, Pengfei Jiang, Xiufang Ye, Menglei Chang, Fuhua Liu, Yuanyuan Shen, Dongchu Chen*, and Libo Nie*, A Novel Suspension Detection of DNA Based on Quantum Dot Encoded Microbeads and Fluorescence Amplifying, Science of Advanced Materials, 2019, 11(5): 680684.

9. Pengfei Jiang, Yulin Wang, Lan Zhao, Chenyang Ji, Dongchu Chen, and Libo Nie*, Applications of Gold Nanoparticles in Non-optical Biosensors, Nanomaterials, 2018, 8(12): 977.

10. Hongcheng Yang, Pengfei Jiang, Zhu Chen, and Libo Nie, Magnetic Fe3O4@Mesoporous Silica Composite Microspheres: Synthesis and Biomedical Applications, Nanoscience and Nanotechnology Letters, 2017, 9(12):18491860.

11. Xiangyun Xiao, Hongcheng Yang, Pengfei Jiang, Zhu Chen, Chenyang Ji, and Libo Nie, Multi-Functional Fe3O4@mSiO2-AuNCs Composite Nanoparticles Used as Drug Delivery System, J. Biomed. Nanotechnol. 2017, 13(10): 1292-1299.

12. Libo Nie, Fuhua Liu, and Hongcheng Yang, Preparation of quantum dot fluorescence encoded polystyrene microbeads, Nanoscience and Nanotechnology Letters, 2017, 9(6)941-944.

13. Libo Nie, Xiangyun Xiao, Hongcheng Yang, Preparation and Biomedical Applications of Gold Nanocluster, Journal of Nanoscience and Nanotechnology, 201616(8): 8164-8175.

14. Libo Nie, Fuhua Liu, Peng Ma, and Xiangyun Xiao, Applications of Gold Nanoparticles in Optical Biosensors, J. Biomed. Nanotechnol. 2014, 10: 27002721.

15. Libo NieZhu Chen, Haojie Zou, and Hao Chang,  Development of Flowing Automatic Quartz Crystal Microbalance System for DNA Detection, Journal of Nanoscience and Nanotechnology, 2013132077-2080

16. Libo Nie, Hao Chang, Zhu Chen, and Quanguo He, Biorecognition on the Surface of Patterned Silicon/Silica and Gold/Silica Slide, Applied Mechanics and Materials, 2012, 220-223: 2991-2995.

17. Libo Nie, Hao Chang, Lian Wei, Zhu Chen, and Ying FengDesigned Pattern Signals of Protein Detection on the Surfaces of Silicon/Silica and Gold/Silica Slides, Advanced Science Letters, 20121811-15.

18. Libo Nie, Xiaoxi Zeng, Huishi Guo, and Liming Zhang, Poly- (N-isopropylacrylamide)-Coated Thermoresponsive/Magnetic/Fluorescent

Multifunctional Microspheres, Advanced science letters, 2012, 10: 202-207.

19. Libo Nie, Liming Zhang, and Zejun WuMagnetic/Polymer/Nanogold Complex Using as a Novel Enzyme SupportJournal of Nanoscience and Nanotechnology, 2011115223-5227.

20. Nie Libo, He Nongyue, Biochips Nanotechnology, Los Angeles American Scientific Publishers2009.

21. Libo NieXiuli Wang, Song Li, Hong Chen, Amplification of fluorescence Detection of DNA Based on Magnetic SeparationAnalytical Sciences, 2009, 25:1327-1331.

22. L B Nie, Y Yang, S Liand N Y HeEnhanced DNA detection based on the amplification of gold nanoparticles using quartz crystal microbalance, Nanotechnology, 200718 551555.  

 

专利:

1. 聂立波,张黎明. 一种金磁核壳纳米粒子的制备方法,专利号:ZL200810026279.5

 

 

 

 

 

 

 

 

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