湖南工业大学生物与医学工程学院专任教师。
2026年毕业于美国纽约州立大学布法罗分校(University at Buffalo, SUNY)生物医学工程专业,获先后理学硕士、博士学位。现主要从事脂质纳米递送材料与系统设计、疫苗工程及免疫调控等方面的研究,致力于构建可用于疫苗及生物活性分子递送的脂质纳米平台。近年来在Journal of Controlled Release、Theranostics、Small、Cancer Immunology Research、Bioactive Materials、Expert Review of Vaccines等SCI期刊发表研究论文和综述十余篇。
1)脂质纳米递送材料与系统设计:脂质体、脂质纳米颗粒及其组成、结构与递送性能调控;
2)疫苗工程与免疫调控:短肽/新抗原疫苗设计、抗原递呈及T细胞免疫调控;
3)生物活性分子的靶向递送:面向疫苗及其他生物活性分子的纳米递送与免疫靶向
暂无。现阶段主要围绕脂质纳米递送、短肽疫苗及免疫调控方向开展科研项目筹备与校院企、医工交叉合作。
(1) Zhou S, Luo Y, Lovell JF, et al. Ganglioside enhances the immunogenicity of nanoparticles displaying short synthetic tumor neoepitopes and epitopes. Theranostics, 2026, 16(10): 5393–5405. DOI: 10.7150/thno.128187.
(2) Zhou S, Song Y Lovell JF, et al. The predominant Quillaja Saponaria fraction, QS-18, is safe and effective when formulated in a liposomal murine cancer peptide vaccine. Journal of Controlled Release, 2024, 369: 687–695. DOI: 10.1016/j.jconrel.2024.04.002.
(3) Zhou S, Luo Y, Lovell JF. Vaccine approaches for antigen capture by liposomes. Expert Review of Vaccines, 2023, 22(1): 1022–1040. DOI: 10.1080/14760584.2023.2274479.
(4) Luo Y, Zhou S, Lovell JF, et al. Iterative selection of lipid nanoparticle vaccine adjuvants for rapid elicitation of tumoricidal CD8⁺ T cells. Bioactive Materials, 2025, 48: 189–199.
(5)He X, Zhou S, Lovell JF, et al. An In Vivo Screen to Identify Short Peptide Mimotopes with Enhanced Antitumor Immunogenicity. Cancer Immunology Research, 2022, 10(3): 314–326.
Tel: 86-15343339633
E-mail: shiqizho@hut.edu.cn